diff --git a/core/clang/TARGET_arm.mk b/core/clang/TARGET_arm.mk
index 5ac5477687..eeffa51f91 100644
--- a/core/clang/TARGET_arm.mk
+++ b/core/clang/TARGET_arm.mk
@@ -69,5 +69,4 @@ $(clang_2nd_arch_prefix)TARGET_LIBPROFILE_RT := $(LLVM_RTLIB_PATH)/libclang_rt.p
 
 # Address sanitizer clang config
 $(clang_2nd_arch_prefix)ADDRESS_SANITIZER_RUNTIME_LIBRARY := libclang_rt.asan-arm-android
-$(clang_2nd_arch_prefix)ADDRESS_SANITIZER_RPATH := /data/vendor/lib:/$(TARGET_COPY_OUT_VENDOR)/lib:/data/lib
 $(clang_2nd_arch_prefix)ADDRESS_SANITIZER_LINKER := /system/bin/linker_asan
diff --git a/core/clang/TARGET_arm64.mk b/core/clang/TARGET_arm64.mk
index 532ca778fa..15b0172a6f 100644
--- a/core/clang/TARGET_arm64.mk
+++ b/core/clang/TARGET_arm64.mk
@@ -67,5 +67,4 @@ TARGET_LIBPROFILE_RT := $(LLVM_RTLIB_PATH)/libclang_rt.profile-aarch64-android.a
 
 # Address sanitizer clang config
 ADDRESS_SANITIZER_RUNTIME_LIBRARY := libclang_rt.asan-aarch64-android
-ADDRESS_SANITIZER_RPATH := /data/vendor/lib64:/$(TARGET_COPY_OUT_VENDOR)/lib64:/data/lib64
 ADDRESS_SANITIZER_LINKER := /system/bin/linker_asan64
diff --git a/core/clang/TARGET_x86.mk b/core/clang/TARGET_x86.mk
index f982439726..9ca86a1956 100644
--- a/core/clang/TARGET_x86.mk
+++ b/core/clang/TARGET_x86.mk
@@ -74,5 +74,4 @@ $(clang_2nd_arch_prefix)TARGET_LIBPROFILE_RT := $(LLVM_RTLIB_PATH)/libclang_rt.p
 
 # Address sanitizer clang config
 $(clang_2nd_arch_prefix)ADDRESS_SANITIZER_RUNTIME_LIBRARY := libclang_rt.asan-i686-android
-$(clang_2nd_arch_prefix)ADDRESS_SANITIZER_RPATH := /data/vendor/lib:/$(TARGET_COPY_OUT_VENDOR)/lib:/data/lib
 $(clang_2nd_arch_prefix)ADDRESS_SANITIZER_LINKER := /system/bin/linker_asan
diff --git a/core/config_sanitizers.mk b/core/config_sanitizers.mk
index df52e7204b..6e968808ce 100644
--- a/core/config_sanitizers.mk
+++ b/core/config_sanitizers.mk
@@ -117,7 +117,6 @@ ifneq ($(filter address,$(my_sanitize)),)
                            $(my_shared_libraries) \
                            $(ADDRESS_SANITIZER_CONFIG_EXTRA_SHARED_LIBRARIES)
     my_static_libraries += $(ADDRESS_SANITIZER_CONFIG_EXTRA_STATIC_LIBRARIES)
-    my_ldflags += -Wl,-rpath,$($(LOCAL_2ND_ARCH_VAR_PREFIX)ADDRESS_SANITIZER_RPATH)
 
     my_linker := $($(LOCAL_2ND_ARCH_VAR_PREFIX)ADDRESS_SANITIZER_LINKER)
     # Make sure linker_asan get installed.