diff --git a/tools/releasetools/target_files_diff.py b/tools/releasetools/target_files_diff.py
index 2cf90513ef..196d2e887c 100755
--- a/tools/releasetools/target_files_diff.py
+++ b/tools/releasetools/target_files_diff.py
@@ -51,6 +51,10 @@ def ignore(name):
               'RECOVERY/RAMDISK/selinux_version']:
     return True
 
+  # b/26956807 .odex files are not deterministic
+  if name.endswith('.odex'):
+    return True
+
   return False