diff --git a/cc/sanitize.go b/cc/sanitize.go
index 92987f7f8..8e0813ddd 100644
--- a/cc/sanitize.go
+++ b/cc/sanitize.go
@@ -430,7 +430,7 @@ func (sanitize *sanitize) begin(ctx BaseModuleContext) {
 	}
 
 	// Enable Memtag for all components in the include paths (for Aarch64 only)
-	if ctx.Arch().ArchType == android.Arm64 {
+	if ctx.Arch().ArchType == android.Arm64 && ctx.toolchain().Bionic() {
 		if ctx.Config().MemtagHeapSyncEnabledForPath(ctx.ModuleDir()) {
 			if s.Memtag_heap == nil {
 				s.Memtag_heap = proptools.BoolPtr(true)
@@ -460,17 +460,17 @@ func (sanitize *sanitize) begin(ctx BaseModuleContext) {
 	}
 
 	// HWASan requires AArch64 hardware feature (top-byte-ignore).
-	if ctx.Arch().ArchType != android.Arm64 {
+	if ctx.Arch().ArchType != android.Arm64 || !ctx.toolchain().Bionic() {
 		s.Hwaddress = nil
 	}
 
 	// SCS is only implemented on AArch64.
-	if ctx.Arch().ArchType != android.Arm64 {
+	if ctx.Arch().ArchType != android.Arm64 || !ctx.toolchain().Bionic() {
 		s.Scs = nil
 	}
 
 	// Memtag_heap is only implemented on AArch64.
-	if ctx.Arch().ArchType != android.Arm64 {
+	if ctx.Arch().ArchType != android.Arm64 || !ctx.toolchain().Bionic() {
 		s.Memtag_heap = nil
 	}