diff --git a/cc/compiler.go b/cc/compiler.go
index 671861b0b..2bc6ae26e 100644
--- a/cc/compiler.go
+++ b/cc/compiler.go
@@ -27,6 +27,10 @@ import (
 	"android/soong/cc/config"
 )
 
+var (
+	allowedManualInterfacePaths = []string{"vendor/", "hardware/"}
+)
+
 // This file contains the basic C/C++/assembly to .o compliation steps
 
 type BaseCompilerProperties struct {
@@ -509,6 +513,12 @@ func (compiler *baseCompiler) compilerFlags(ctx ModuleContext, flags Flags, deps
 		flags.Local.CFlags = append(flags.Local.CFlags, "-fopenmp")
 	}
 
+	// Exclude directories from manual binder interface whitelisting.
+	//TODO(b/145621474): Move this check into IInterface.h when clang-tidy no longer uses absolute paths.
+	if android.PrefixInList(ctx.ModuleDir(), allowedManualInterfacePaths) {
+		flags.Local.CFlags = append(flags.Local.CFlags, "-DDO_NOT_CHECK_MANUAL_BINDER_INTERFACES")
+	}
+
 	return flags
 }
 
diff --git a/cc/makevars.go b/cc/makevars.go
index e8cedf0f6..0f9f4c1e1 100644
--- a/cc/makevars.go
+++ b/cc/makevars.go
@@ -147,6 +147,7 @@ func makeVarsProvider(ctx android.MakeVarsContext) {
 	ctx.Strict("WITH_TIDY_FLAGS", "${config.TidyWithTidyFlags}")
 
 	ctx.Strict("AIDL_CPP", "${aidlCmd}")
+	ctx.Strict("ALLOWED_MANUAL_INTERFACE_PATHS", strings.Join(allowedManualInterfacePaths, " "))
 
 	ctx.Strict("M4", "${m4Cmd}")