diff --git a/rust/bindgen.go b/rust/bindgen.go
index 845f2586d..32d02e4f6 100644
--- a/rust/bindgen.go
+++ b/rust/bindgen.go
@@ -15,6 +15,7 @@
 package rust
 
 import (
+	"fmt"
 	"strings"
 
 	"github.com/google/blueprint"
@@ -147,6 +148,31 @@ func (b *bindgenDecorator) GenerateSource(ctx ModuleContext, deps PathDeps) andr
 	cflags = append(cflags, strings.ReplaceAll(ccToolchain.Cflags(), "${config.", "${cc_config."))
 	cflags = append(cflags, strings.ReplaceAll(ccToolchain.ToolchainCflags(), "${config.", "${cc_config."))
 
+	if ctx.RustModule().UseVndk() {
+		cflags = append(cflags, "-D__ANDROID_VNDK__")
+		if ctx.RustModule().InVendor() {
+			cflags = append(cflags, "-D__ANDROID_VENDOR__")
+		} else if ctx.RustModule().InProduct() {
+			cflags = append(cflags, "-D__ANDROID_PRODUCT__")
+		}
+	}
+
+	if ctx.RustModule().InRecovery() {
+		cflags = append(cflags, "-D__ANDROID_RECOVERY__")
+	}
+
+	if mctx, ok := ctx.(*moduleContext); ok && mctx.apexVariationName() != "" {
+		cflags = append(cflags, "-D__ANDROID_APEX__")
+		if ctx.Device() {
+			cflags = append(cflags, fmt.Sprintf("-D__ANDROID_APEX_MIN_SDK_VERSION__=%d",
+				ctx.RustModule().apexSdkVersion.FinalOrFutureInt()))
+		}
+	}
+
+	if ctx.Target().NativeBridge == android.NativeBridgeEnabled {
+		cflags = append(cflags, "-D__ANDROID_NATIVE_BRIDGE__")
+	}
+
 	// Dependency clang flags and include paths
 	cflags = append(cflags, deps.depClangFlags...)
 	for _, include := range deps.depIncludePaths {
diff --git a/rust/rust.go b/rust/rust.go
index a3702d815..4a43c3eb4 100644
--- a/rust/rust.go
+++ b/rust/rust.go
@@ -163,6 +163,9 @@ type Module struct {
 	docTimestampFile     android.OptionalPath
 
 	hideApexVariantFromMake bool
+
+	// For apex variants, this is set as apex.min_sdk_version
+	apexSdkVersion android.ApiLevel
 }
 
 func (mod *Module) Header() bool {
@@ -678,6 +681,10 @@ func (mod *Module) installable(apexInfo android.ApexInfo) bool {
 	return mod.OutputFile().Valid() && !mod.Properties.PreventInstall
 }
 
+func (ctx moduleContext) apexVariationName() string {
+	return ctx.Provider(android.ApexInfoProvider).(android.ApexInfo).ApexVariationName
+}
+
 var _ cc.LinkableInterface = (*Module)(nil)
 
 func (mod *Module) Init() android.Module {
@@ -1023,6 +1030,20 @@ func (mod *Module) depsToPaths(ctx android.ModuleContext) PathDeps {
 	directSrcProvidersDeps := []*Module{}
 	directSrcDeps := [](android.SourceFileProducer){}
 
+	// For the dependency from platform to apex, use the latest stubs
+	mod.apexSdkVersion = android.FutureApiLevel
+	apexInfo := ctx.Provider(android.ApexInfoProvider).(android.ApexInfo)
+	if !apexInfo.IsForPlatform() {
+		mod.apexSdkVersion = apexInfo.MinSdkVersion
+	}
+
+	if android.InList("hwaddress", ctx.Config().SanitizeDevice()) {
+		// In hwasan build, we override apexSdkVersion to the FutureApiLevel(10000)
+		// so that even Q(29/Android10) apexes could use the dynamic unwinder by linking the newer stubs(e.g libc(R+)).
+		// (b/144430859)
+		mod.apexSdkVersion = android.FutureApiLevel
+	}
+
 	ctx.VisitDirectDeps(func(dep android.Module) {
 		depName := ctx.OtherModuleName(dep)
 		depTag := ctx.OtherModuleDependencyTag(dep)